Trazodone Hcl (Desyrel®) is an antidepressant
for patients whose depression has not responded
to other medications, or who have experienced side
effects with other antidepressants. Trazodone is
also be used to treat sleep and insomnia problems,
anxiety, and panic attacks. Trazodone tablets
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Trazodone Hydrochloride Information
Uses of Trazodone Hydrochloride
Trazodone Hydrochloride is used primarily for
the treatment of depression; however, it is sometimes
prescribed as a sedative, and in the treatment
of cocaine withdrawal. Trazodone hcl is also used
in combination with other drugs for the treatment
of psychiatric conditions other than depression.
Trazodone Hcl Directions
Take Trazodone with food (or shortly after eating
food). The initial starting dose usually is 150mg
per day. Dosages are usually adjusted slowly upwards
from 50mg-100mg to find the optimal dose. In the
treatment of depression the dose for adults is
150-600 mg per day. Trazodone is given with the
largest dose at night. As with all antidepressants,
it may take several weeks for the full effects
of your treatment to occur.
Trazodone Hcl Side Effects
Side effects sometimes associated with trazodone
Hydrochloride are nausea, dizziness, insomnia,
lightheadedness, headache, low blood pressure,
agitation, tiredness, dry mouth, constipation,
blurred vision, and confusion. Priapism (including
clitoral priapism in women), a painful condition
in which the penis (or clitoris) remains in an
erect position, has been reported in patients receiving
trazodone. Priapism can result in permanent impairment
of erectile function or impotence, so attend emergency
room treatment as soon as possible. Patients should
be warned of the possibility of priapism and told
to discontinue the drug at once and consult with
their physician if this reaction occurs. Trazodone
also may affect ejaculation, orgasm and libido.
Trazodone Hcl Precautions
All antidepressants that increase concentrations
of serotonin in the brain, like trazodone, should
not be taken with MAO-inhibitors like isocarboxazid
(Marplan), phenelzine (Nardil), tranylcypromine
(Parnate), and procarbazine (Matulane). Such combinations
may lead to confusion, high blood pressure and
tremor. This same type of interaction may occur
when trazodone is used with selegiline (Eldepryl).
If a patient is switched from trazodone to an MAO
inhibitor, at least one week should be allowed
after stopping the trazodone before the MAO inhibitor
is begun.
Trazodone Hcl Notes
There are no adequate studies of trazodone in
pregnant women. Studies in animals have demonstrated
effects on the developing fetus. Trazodone should
only be used during pregnancy if the physician
feels that its benefits outweigh its potential
risks. Trazodone is secreted in breast milk. Therefore,
caution should be used in prescribing trazodone
to women who are breast- feeding. Take your missed
dose of Trazodone Hcl as soon as you remember.
Additional Trazodone Information:
PsyWeb:
Trazodone (Desyrel) Data Sheet
DESYREL®
(trazodone HCl) : Trazodone Monographs including
chemistry, chemical structure and ingredients
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